11 replies to this topic

[Razor D]

got bad news yesterday, a bro of mine has colon cancer, was curios if test would do any good ,i know its not a cure or anything , but would it make it worse,cause i know it would make him feel better,also any helpful ideas would be appreciated ,i know we have some smart cats around here.plan on putting him on lots of antioxidants like vitamin c ,and liv-52


thanks
razor d

[any1uno]

I'm sorry for your loss Ms Diesel.

As well as I'm sorry for the news about your friend.

I would suggest that your friend discuss HRT with his doctor. At this stage of the game it would be best to have him do so. It is a good plan to have him taking antioxidents. For Colon cancer you may want to do a little research to make sure that everything he takes will not add to the problem.

Liv 52 tabs are a great idea for Liver protection. I can look around to see if I can find anything more.

If you knew how far along the cancer is that would help. If caught early enough there are treatments that will pretty much take care of this. Also...a good positive attitude will help as I feel the mind has a lot to do with one's health and well being. Keep your friend positive and support him while he faces this problem..one day at a time.

[Grunt76]

Grapeseed extract is known to specifically attack cancer cells.

I believe it is most effective against gender cancers such as breast, ovary, testicle, etc. but it MAY be effective against colon, I do not know.

Some high doses would be recommended. I would go with a bulk purchase at kalyx.com, which has a whole kilo for $135... And up to 25kg...

[ruffneck]

I would not recomend any gear until it is discussed with his cancer doctor. There are different type of cancer cells and in some cases test can increase the rate at which it spreads.

[deadweight]

This topic is one of my many fears.....I have no comment except ........I wish this was a fairy tale....

[Rage101]

one advantage of AAS would be preserving lean body mass. The wasting away that is associated with cancer can be a major factor. Also look in to GH and it's positive effects on the immune system, the immune system helps fight cancer.

You do need to find out more specifics about what type of cancer he has exactly.

[gator_mclusky]

Fortuneately my friends dads was caught in time.

Personally I would not recommend Test. Overabundance of Test can lead to enlargement of the Prostate, then Cancer. If it promotes it in the Prostate then it may have those same capabilities elsewhere.
Definately have him discuss it with his doctor or if his Doc isnt all that cool, have him see an Endocrinologist.
Prayers that way.

Gator

[razg]

If you are going to do anything, please do not give this person stuff via your own recommendations. Nor that of the board, example:

GH has been suggested - GH increases the rate of cell differentiation (in jargon-free terms, cancer grows faster). Test is also suppressive of the immune system.

I think a better course of action would be to personally hunt down a doctor who has interests in alternative/nutritional therapy as well as being medically qualified. You don't risk the doubled edged sword then. Even best intentions can cause harm.

[Rage101]

GH has been suggested - GH increases the rate of cell differentiation (in jargon-free terms, cancer grows faster). Test is also suppressive of the immune system.

What if it is a non-differentiated or poorly differentiated cancer? Are you suggesting GH will change it to a well differentiated cancer?

the GH effect applies mostly to cells that are normal. think about it, for example if a colon cancer has a defective DCC tumor supressor gene on chromome 18q taking away the limit on cell proliferation do you think GH is really going to speed it up any more if it is already maxed out?

I'd like to hear your pathophysiologic explanation on this one please.

If you are going to do anything, please do not give this person stuff via your own recommendations. Nor that of the board

I do agree with that statement. this is someones life we are talking about. any suggestion should be completely evaluated and researched, then discussed with your physician.

[razg]

What if it is a non-differentiated or poorly differentiated cancer? Are you suggesting GH will change it to a well differentiated cancer?

the GH effect applies mostly to cells that are normal. think about it, for example if a colon cancer has a defective DCC tumor supressor gene on chromome 18q taking away the limit on cell proliferation do you think GH is really going to speed it up any more if it is already maxed out?

I'd like to hear your pathophysiologic explanation on this one please.

I don't get what you're saying, sorry. This abstract implies the role of GH in colorectal cancer; moreover the increased IGF-1 levels have been linked time and time again with tumor growth.

[Growth hormone receptor expression in human colorectal cancer and its implication]

Yang XD, Liu FK, Xu Z, Li JS.

Research Institute of General Surgery, Nanjing General Hospital of PLA, Nanjing 210002, China. yangxd96@hotmail.com

OBJECTIVE: To investigate the role of the expression of growth hormone receptor (GHR) in the development and progression of human colorectal cancer (CRC). METHODS: The expression levels of GHR and Ki-67 were detected by immunohistochemistry technique in CRC specimens and normal mucous tissue from 100 patients with CRC. The association between expression of GHR and clinicopathological factors was analyzed. RESULTS: The expression of GHR was higher in the colorectal cancerous tissue compared to the normal mucous tissue (81% vs. 68%). The expression of GHR was significantly correlated with pathological staging (P=0.047), tumor differentiation (P=0.003) and tumor size (P=0.017). The expression of GHR was significantly associated with the expression of Ki-67 (P< 0.01) as well as tumor proliferation (P< 0.01). CONCLUSION: The over-expression of GHR is shown in human colorectal cancer and it also plays an important role in the development of human colorectal cancer. The use of rhGH in clinic should be cautious.

PMID: 16167241 [PubMed - in process]

[Rage101]

Can you post that whole article or give me a link to it? yes, it does say that use of GH should be used cautiously.

What part of my question was unclear? I can try to explain what I was asking.

[Rage101]

Here is part of an equally interesting abstract... Almost a contrasted view to what your article suggests. I don't want to quarrel, I just think this one makes an interesting discussion. granted, this one does not discuss colon cancer. I find it odd that GH can increase IGF (which may or may not have something to do with cancer) and also induce apoptosis mediators.

Perturbations of the insulin-like growth factor (IGF) axis, including the autocrine production of IGFs, IGF binding proteins (IGFBPs) and IGFBP proteases such as prostate specific antigen (PSA), and cathepsin D have been identified in prostate, lung and breast cancer cells and tissues. Serum IGFBP-3 levels have been found to be negatively correlated to the risk of cancer. Interestingly, IGFBP-3 is a potent inhibitor of IGF action and also mediates apoptosis via an IGF-independent mechanism. Recent case-control studies have found an approximately 10% increase in the serum levels of IGF-I in patients with prostate, breast and lung cancers, which are among the most frequently diagnosed cancers. While the studies indicate an association between serum IGF-I levels and cancer risk, causality has not been established. Thus, serum IGF-I level may actually be a confounding variable, serving as a marker for autocrine tissue IGF-I production. Growth hormone (GH) therapy raises both IGF-I and IGFBP-3 levels in serum.